The Protein facility of the Netherlands Cancer Institute started its activities in 2008 and shares lab space and equipment with the structural biology groups of Anastassis Perrakis and Titia Sixma at the Division of Biochemistry (B8). The facility offers an excellent infrastructure for biochemical, biophysical and structural biology experiments and contributes to a variety of research projects. Projects can be submitted to the facility (see contact details below) and will be discussed in terms of costs and feasibility before initiation of the project. Projects are classified as short-term (less than 3 days of work) and long-term (more than 3 days of work). For long-term projects hands-on assistance from the applicant is required. The activities of the facility can be subdivided into different categories.

Construct design and cloning
Protein production
Protein purification
Antibody production
Biophysical characterization
Crystallization screening
Mass spectrometry