North Shanghai Yi Biotechnology Co., Ltd. (Shanghai New Drug Safety Evaluation and National Research Center) was established in 1993 , is established under the national “Nine Five” key construction projects financed 5 national GLP one of the centers, formerly known as the Shanghai pharmaceutical industry Research Institute of Pharmacology and toxicology, pharmacology and toxicology research in 40 years. As China’s first and most comprehensive preclinical safety evaluation research institutes, centers in 2003 became the first in China by the CFDA ’s GLP certification body, then centers have adopted the international animal experiments Assessment and Accreditation Council ( AAALAC ) fully certified by OECD member Government of the Netherlands GLP fully certified by the US FDA ’s GLP inspection by the College of American pathologists CAP certification, product testing by the Shanghai quality and Technical Supervision qualified certification bodies (CMAF certification), China national accreditation Board qualification certification ( CNAS certification).