Since the 1996 Olympics in Atlanta, the Analytical Laboratory has operated as a shared facility between the Department of Pharmacology and Toxicology and the Clinical Research Center. In addition, investigators from the NASA Space Medicine and Life Sciences Research Center at Morehouse School of Medicine also extensively used the analytical chemistry laboratory. The CRC has recently realigned and consolidated the analytical core with the proteomics core laboratories to become the Analytical and Protein-Profiling Core, a virtual umbrella or super core, similar to other institutional research cores. For both basic and clinical investigators, the Analytical and Protein Profiling Laboratory will be a multifunctional resource providing analytical consultation, help in the preparation of manuscripts and proposals as well as sample analysis. This administrative structure ensures uniformity in investigator utilization, a common platform for marketing of services, thus promoting access, and increased utilization. The revised structure also allows investigators to access and view all MSM research core labs “at a glance”. Problems arising due to variations in methods between laboratories can be avoided.