The mission of the W.M. Keck Metabolomics Research Laboratory (MRL) is to provide researchers services that enable the high-throughput chemical analysis of metabolites and metabolism. The MRL is equipped with a variety of state-of-the-art analytical instruments that provide researchers with analytical flexibility to analyze a diverse set of metabolites with a variety of chemical and physical properties. The MRL has the capacity to conduct these types of analyses on a 24-hour a day, 7-days a week basis. The establishment of the MRL was made possible by a grant from the W.M. Keck Foundation.