Integral Molecular (www.integralmolecular.com) provides specialized membrane protein reagents and antibody characterization services to enable therapeutic discovery against membrane proteins, an important group of drug targets found on the surfaces of cells and viruses. With nearly 20 years of experience, Integral Molecular is the leading provider of membrane protein solutions.

Integral Molecular’s Membrane Protein Solutions Include:

• Reporter Virus Particles (RVPs): Integral Molecular offers pseudotyped Reporter Virus Particles to test virus neutralization by antibodies or sera in a safe, BSL-2 environment. RVP offerings include GFP and luciferase SARS-CoV-2 and >70 variant RVPs (including Omicron), SARS-CoV-1, MERS-CoV, dengue serotypes 1-4 and Zika.

• Membrane Proteome Array: Antibody screening against 6,000 unfixed human membrane proteins for specificity profiling and target identification.

• Lipoparticles: Our virus-like particles contain high levels of native membrane proteins for better immunization, screening, and characterization.

• MPS Antibody Discovery: The Membrane Proteins Solutions (MPS) Antibody Discovery platform is a full suite of services optimized to deliver functional MAbs against complex membrane proteins with a > 95% success rate.

• Shotgun Mutagenesis Epitope Mapping: Our Ala-scan conformational epitope mapping service measures the precise binding of an antibody to the target within intact cells. This offering enables lead candidate selection by uncovering mechanisms of action and helps strengthen intellectual property.