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InnoSIGN

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Year Established:
2022
Website:
innosignbio.com
Headquarters:
Mason, Ohio, US
Company Type:
New Startup (0-1M TTM Revenue)
Certifications:

InnoSIGN offers its OncoSIGNal technology to gain insight into the functional activity of cellular signaling pathways. mRNA levels transcribed from direct target genes regulated by the pathway transcription factors are translated into pathway activity scores for the ER, AR, PI3K, MAPK, Hedgehog, TGFß, Notch, Wnt, NF-kB and JAK-STAT1/2 pathways, resulting in a quantitative characterization of the cell molecular phenotype.

OncoSIGNal is available for clinical use in breast cancer as a lab-developed test through InnoSIGN’s CLIA laboratory in Mason (OH), for research use through labs in the EU and US as a comprehensive testing service, or as a distributed PCR test for use in a customer laboratory.

The analysis can also be run from RNA-seq data for various cancer and cell types. InnoSIGN utilizes its extensive database with more than 100,000 pathway activity profiles to support drug and diagnostics development.

OncoSIGNal Products & Services for Research-Use-Only

OncoSIGNal Test (G7)

  • ER, AR, PI3K, MAPK, Hedgehog, Notch, TGFß pathways
  • Compatible with FFPE samples from human origin
  • RT-qPCR testing plates including quality checks on sample input and correct plate filling
  • Result overview in dedicated OncoSIGNal Report
  • Allows for in-house testing using standard laboratory equipment
  • Developed under ISO13485

OncoSIGNal Service Testing

  • ER, AR, PI3K, MAPK, Hedgehog, Notch, TGFß and/or Wnt, NF-kB and JAK-STAT1/2 pathways
  • Compatible with FFPE tissue samples and RNA extracted from cell lines and tissue of human origin
  • Extensive quality checks on samples, laboratory process and results
  • Result overview in dedicated OncoSIGNal Report
  • ISO13485 certified

OncoSIGNal Data Service

  • ER, AR, PI3K, MAPK, Hedgehog, Notch, TGFß and/or Wnt, NF-kB and JAK-STAT1/2 pathways
  • Analysis of full transcriptome RNA sequencing data
  • Compatible with FASTQ data files
  • Extensive quality checks on samples and results
  • Result overview in dedicated OncoSIGNal Report

OncoSIGNal Laboratory Developed Test for clinical use

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InnoSIGN INC
5155 Financial Way Mason, Ohio, 45040 United States
InnoSIGN BV
High Tech Campus 11 Eindhoven, , 5656AE Netherlands
InnoSIGN Inc CLIA laboratory
5155 Financial Way Mason, Ohio, 45040 United States

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