Here at Human Cell Design, we are convinced that human cell models are the way forward to getting better medication to patients faster:

- We are a CRO specialists in human beta cells culture (>20 years)
- We have a unique terminal maturation platform to have a large quantity of mature cells
- We have a unique modelization EndoC-βH5 platform to create genome edited cells
- We perform custom human primary-based cell services
- We have been recognized by >450 labs worldwide & >160 peer reviewed publications

We propose a large number of custom services:

- Production of genome edited EndoC-βH5: Model your cells with ADAPT® platform
- Target discovery: Target identification and validation
- Compounds screening: GLP1-R/GIP agonist screening, IC50
- Disease modelling: IC50, inflammation, T1D T-cell killing, T2D glucolipotoxicity
- Specific assay development: Reporter genes, luminescence, microscopy, specific readouts, …

As well as different beta cell models:

- EndoC-βH1: Immortalized beta cells for proliferation assays
- EndoC-βH5: Mature naive-like cells for functional assays
- EndoC-βH5 HLA-A2: T1D-specific disease model for T-cell killing assays
- EndoC-βH5 GLTx: T2D-specific disease model for glucotoxicity assays