At the Houston Methodist Biostatistics Core, we provide statistical analysis, data management and high performance computing services to internal and external research teams. Our core is a fee-for-service facility that consults on study design and analyses for grant- and contract-supported investigative research teams and clinical research groups. Our staff — who together hold more than 50 years experience in statistical analysis, mathematics, computation and data management — participate in grants, contracts, teaching and private consultations. We offer help in the areas of:

Study design and conceptualization
Data collection, storage/retrieval, and warehousing
Sample size determination and statistical power
Percentage points for discrete and continuous probability distributions (Binomial, Poisson, Standard Normal, Student’s t, F-ratio, Laplace, Skew-Normal, Logistic, etc.)
Monte Carlo simulation and uncertainty analysis
Inferential hypothesis testing
Linear models (ANOVA, ANACOVA, MANOVA, and regression)
Categorical modeling (log-linear, linear categorical, regression, and logistic regression)
Univariate and multivariate regression modeling and diagnostics
Survival and propensity scoring analysis
Longitudinal data analysis (GLM, GEE, and RMANOVA)
Bioinformatics (microarray QC, normalization, gene profile identification, cluster, and heat maps)
Data mining