The Functional Genomics Center Zurich (FGCZ) is a joint state-of-the-art research and training facility of the ETH Zurich and the University of Zurich. With the latest technologies and key expertise for Omics research, the FGCZ carries out research projects and technology development in collaboration with the Zurich Life Science research community.

Genomics:
Illumina Sequencing Full Services: Project planning to data analysis. We start by discussing your project. You provide the biological know-how and we bring the NGS expertise. Based on our discussion, we will perform the library preparation, sequencing, and basic data analysis.

Single Cell Sequencing: We offer technologies that can examine the sequence information from individual cells

Spatial Transcriptomics: Whole transcriptome and targeted spatial profiling solutions starting with sectioned tissues.

Long Read Sequencing: We offer full package services including project discussion, DNA/RNA quality Control, Library Preparation, Sequencing, and data QC. Downstream Data Analysis is provided upon request.

Whole Genome Imaging – Optical Mapping: We offer access to the Bionano Saphyr workflow in user lab mode

Genome Informatics: Whether you have an established or a customized implementation of advanced models and algorithms, we run them all

Genome Engineering:

Proteomics:
Proteome Identification and Quantification: We support proteomics projects from initiation to final data analysis. This includes project discussions, sample preparation, mass spectrometry, and bioinformatics analyses

Interaction Proteomics:
Our interaction proteomics packages include project discussion, mass spectrometry, and bioinformatics analyses. Protein interaction partners can be identified and quantified by: Affinity purification mass spectrometry (AP-MS) and Proximity labeling (BioID, TurboID, APEX)

Characterization of purified biomolecules:
We combine mass determination and proteomics approaches for the characterization of purified biomolecules. Examples include: determine the molecular weight of intact proteins (incl. antibodies), confirm the identify of a protein, analyse protein-​metal complexes, characterize protein disulfide bridges and N-​termini, identify protein post-​translational modifications and characterize oligonucleotides