Edelris
Year Established:
2005 |
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Website:
edelris.com |
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Headquarters:
Lyon, FR |
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Company Type:
Small Business (1-10M TTM Revenue) |
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Completed Requests:
7 |
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Open Requests:
12 |
Hit Generation: Edelris offers premium services in Hit Generation:
- Keymical Fragments: non-exclusive 3D fragments for Fragment-based lead discovery (FBLD/FBDD). These innovative compounds are tractable, Natural-by-Design (purely synthetic compounds accessible in a few reliable steps from commercially accessible starting material), and have proven successful in many FBS campaigns at clients’.
See for example: https://doi.org/10.1016/j.bmcl.2019.126717 and http://practicalfragments.blogspot.com/2020/01/three-dimensional-fragments-revisited.html
- Keymical Collections: non-exclusive 3D lead-like series of compounds for HTS. These innovative compounds are tractable, Natural-by-Design (purely synthetic compounds accessible in a few reliable steps from commercially accessible starting material), and have proven sucessful in many screening campaigns at clients’.
See for example: H.Waldmann et al. Angew. Chem. Int. Ed. 2019, 58, 17016 – 17025
- EDEN (Edelris Discovery ENgine): based upon an in-house designed and produced screening collection of 2 million compounds from its Keymical Space, Edelris offers efficient ligand identification services using AS-MS (Affinity Selection – Mass Spectrometry), against biological targets from clients. Edelris has successfully screened dozen of targets ranging from enzymes, native GPCR, RNA, PPI…
Clients screening decks can also be used, blinded if needed.
- DEL by EDELRIS: DNA-encoded libraries for exclusive clients applications
Hit-to-Lead, Lead Optimization: Edelris offers cost-efficient and track-proven medicinal chemistry services (Hit exploration, fast follow-up library synthesis, iterative optimization loops) towards an overall biological profile defined by the clients.
See for example: https://doi.org/10.1021/acschembio.7b00708
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EDELRIS 60, Avenue Rockefeller Lyon, , 69008 France |
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