Dualsystems Biotech is a service provider for custom proteomics for industry and academia. We are a biotech company specialising in elucidating protein-protein interaction in the living cells focussing at the cell membrane. We identify the targets of your extracellular ligands using the ligand-receptor capture LRC-TriCEPS™ technology. During the interaction of your ligand of interest and its unknown targets and off-targets the cells are still alive and the unknown targets are in their natural microenvironment.

The LRC-TriCEPS™ platform can also be used to identify new drug targets by identifying new cell-cell interactions also on primary cells (analogue to PD-1/PDL-1 interactions of T-cells with tumor cells).

With Flow-TriCEPS™ (Prestest TriCEPS™) we provide a tool to use in flow cytometry to identify the best binding conditions for your ligand of interest without the need of a detection antibody. Further, it can be used to identify the the best conditions for the expression of the unknown targets. Flow-TriCEPS can be used in functional assays to test if a TriCEPS coupled ligand is functionally active. Flow TriCEPS couples the ligand by using primary amines (N-Term and Lysines) and since it contains a biotin, can be detected by a streptavidin fluorophore conjugate using flow cytometry.