Toxicity testing and model development in vitro with a focus on developmental and adult neurotoxicity.

DNTOX GmbH uses human cell models and enables artificial intelligence-based screening with in-house developed software.
The in vitro test system is comprised of a set of multicellular test methods that are based on human neural progenitor cells (hNPCs) and human induced pluripotent stem cells (hiPSCs). These cells are cultivated as free-floating or plated and adherent 3D spheres as well as 2D monolayer cultures. Our cell models can be used to study several key neurodevelopmental and neuronal processes.