The In Vivo Multiphoton/Confocal Microscopy Core provides a cutting-edge, two-photon/confocal hybrid microscope system that allows visualization of dynamic movement and location of fluorescence-labeled cells in live animals.

Our in vivo multiphoton/confocal microscopy is advantageous in the following analyses:

Video-rate, or 3D time-lapse movie for the analysis of dynamic cellular behavior in live animals;
3D analysis of cell location in live animals;
Subcellular-resolution imaging with weak fluorescent signals in deep tissues made possible by a multi-photon laser and 2 non-descanned detectors;
Multicolor imaging (theoretically over seven colors) made possible by five single-photon lasers (458, 488, 514, 561, 633nm), one multi-photon laser, and seven detectors;
Fast scanning of a large area with a resonance scanner (over 60 frames per second) is advantageous for the analysis of rare cell populations (e.g. stem cells).
The director and the manager provide assistance for the experimental design, and the data interpretation. The manager operates the microscope for the user.