The Center for Radiological Research, directed by Gary Johnson, offers the most comprehensive design and instrument shop in the Columbia-Presbyterian Medical Center complex. Established in 1947, the facility has been continuously modernized and updated. Using a CAD (computer aided design) system, specialized, complex, custom-made instrumentation and equipment of almost any physical size, including micro-machining of plastics, metals, and ceramics, can be fabricated. Consultation with, and guidance for researchers is provided in determining appropriate materials and design, along with technological advice and suggestions. The shop is also equipped for micro-brazing and micro-silver soldering, as well as for plastic molding and mechanical repair of small laboratory equipment.