The Genomics Core is focused on gathering genome, transcriptome, epigenome and metagenome information for investigators. Our mission is to make these complex technologies accessible and biologically interpretable for clinical and basic research scientists.

The Genomics Core enables investigators with little experience in sample preparation, quality control, or analysis to interrogate the genome. To facilitate this, we have developed general but complete wet-lab and bioinformatics analysis pipelines to accommodate standard needs and enable most genome-wide investigations. For more sophisticated or custom designs, we work actively in collaboration with other Cedars-Sinai cores and resources to facilitate investigations.

The Genomics Core now offers new applications, such as single-cell RNA sequencing, microbiome profiling and targeted transcriptome resequencing for FFPE samples, using a brand-new Illumina NextSeq, Illumina MiSeq and an Ion Proton Sequencer. The combination of instruments enables us to uniquely identify the best solutions for each project depending on sample size, sample quality, price and turnaround time.