Biospective is a leading Preclinical Contract Research Organization (CRO) specializing in Neuroscience research studies. We have extensively validated and readily available rodent models of ALS (TDP-43), Alzheimer’s disease (beta-amyloid and tau), Parkinson’s disease (alpha-synuclein), and multiple sclerosis (EAE and cuprizone). We offer a wide range of services to evaluate therapeutic agents in these models, including dosing, motor & sensory function, cognition & sleep, electrophysiology, fluid & cellular biomarkers, in vivo imaging (MRI, CT, PET, SPECT), image processing, image analysis, histology, IHC, multiplex immunofluorescence, and spatial biology analysis.