BioMedha is a UK-based pre-clinical CRO providing in vitro biology expertise to the global drug discovery industry. We are industry-experienced, in vitro biology-focused scientists and can add significant value to our client programmes by undertaking key elements of the early stage drug discovery process. BioMedha expertise includes:
• Access to fresh whole blood, Whole blood assays
• Immune cell isolation and differentiation supporting functional assays
• Immunology, Oncology, Immuno-oncology, and inflammation studies
• Target validation, assay development, and compound screening, and Mechanism of action studies
• Flow cytometry capabilities
• Luminex based Cytokine assays and multiplexing
• Cell imaging expertise
• Expression studies (protein levels by western blot/ELISA, mRNA levels by qPCR, and surface expression by Flowcyte)
• Clariostar Multimode plate reader-based assays (Fluorescence, Luminesce, FP, FRET, BRET, Alphascreen, HTRF)
• Functional Studies (e.g. signalling pathways, bioassays)
• GPCRs: Assay development and screening
• Protein-Protein Interactions (PPI)
• Enzyme activity
• Discovery Toxicology studies