Biognosys offers services and tools that cover two distinctive research areas for protein analysis needs: discovery and targeted proteomics. Biognosys’ discovery proteomics platform allows for quantification of thousands of proteins per sample and is well suited for identifying statistically relevant protein abundance changes at the proteome level without the need for any previous knowledge of specific protein biomarkers. In contrast, Biognosys’ targeted proteomics platform provides an accurate quantification screening method (absolute or relative) for up to 150 pre-defined protein biomarkers that can be analyzed in a high throughput fashion, for up to several thousand samples.

The most popular service offering that Biognosys provides to its clients is its proprietary Next-Generation proteomics profiling analysis using Hyper Reaction Monitoring (HRM) technology, which provides unmatched proteome coverage with reproducible and precise quantification that can reach up to 9’000 proteins per sample. The HRM discovery service offering is ideal for identifying differentially expressed proteins from a wide variety of biological sample types and species (i.e. cell lines, tissues, serum/plasma, CSF, plant and microbe). The highly multiplexed, quantitative proteomic results that are obtained from these types of studies are ideally suited for downstream bioinformatics analysis, such as hierarchical clustering to confidently identify protein biomarker signatures that can be used to correlate against a particular phenotype, a specific disease condition or as an indicator for appropriate drug response. Biognosys has led the development of Next- Generation proteomics and is committed to enable others to adopt this transformative technology for deep, proteome quantitation through the use of its software and product offerings as well.