Bio-Mimetic Chromatography Ltd offers HPLC based bio-mimetic property measurements for drug discovery compounds. it includes protein and phospholipid binding as well as lipophilicity of the compounds at three different pH. Based on the data we estimate and rank in-vivo properties of the compounds based on published and validated models. These models include volume of distribution, drug efficiency, brain tissue binding, lung tissue binding, skin absorption, blood/brain distribution, phospholipidotic potential, cellular accumulation. We offer consultancy to setup these measurements and we are offering developing new local models based on the client’s compounds data.

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