The Human Immunophenotyping Core Laboratory (HIP-c) at Benaroya Research Institute (BRI) is designed to facilitate the study of human immune-mediated diseases through helping identify underlying mechanisms of disease, developing biomarkers of disease and targeting therapeutic intervention. This is done through the use of standardized, reproducible assays appropriate for application to large sample sets or rare/precious human samples including:

surface, intracellular and phospho-flow cytometry
CyTOF
cell selections
DNA and RNA isolation
ELISA’s
Luminex assays
short-term in vitro assays (i.e. proliferation, cytokine secretion, activation)
ELISpot
qPCR

Centralization of these assays on human samples limits variation between labs making data more comparable between investigators, facilitates data sharing by enabling linkage of clinical, genetic, genomic and immunological parameters to each sample studied and enhances collaboration between clinicians and scientists.