Mimetas develops human tissue and disease models for better therapies in OrganoPlates®. We all want better medicines, that’s obvious. To make this possible, you need better disease models. They should be fully human and physiologically relevant. Truly informative tools, compatible with compounds and with your high-throughput readout equipment. And of course you need them today, rather than tomorrow. A dream? Not anymore. As true pioneers in organ-on-a-chip biology, MIMETAS is proud to offer high-throughput human tissue and disease models in OrganoPlates®.

OrganoPlates® are microfluidic 3D culture plates, supporting up to 96 tissue models on a single plate. OrganoPlates® contain Phaseguides, a proprietary, passive liquid handling technology for membrane-free definition of tissues in microfluidic chambers. OrganoPlates® are based on the industry-standard 384-well plate for full compatibility with liquid handling- and readout equipment. Within the plate, cells are contained in a gel, supporting 3D tissue configurations and cell-cell interactions. A continuous perfusion of media through the plate mimics blood flux and exchange of nutrients, oxygen and metabolites. The plates are versatile, supporting chemical gradients and co-culture conditions. In this way, complex tissue models can be implemented in a straightforward way.