The Gastrointestinal Cancer Research program at the Baylor Research Institute, has a broad research focus on understanding the molecular pathogenesis of human gastrointestinal cancer, and as it relates to cancer prevention. More specifically, the major objective of our research involves deciphering the interplay between genetic and epigenetic alterations in sporadic and familial (e.g. Lynch syndrome, familial adenomatous polyposis, serrated polyposis) forms colorectal cancer, and other gastrointestinal cancers (gastric, pancreatic and hepatocellular). The broad mission of the research program is to:
Conduct high quality research into the pathogenesis of colorectal cancer
Develop clinically useful biomarkers for the early detection of colorectal polyps and cancer
Develop clinically useful biomarkers that can help direct therapeutic treatments for patients with colorectal cancer
Use complementary and alternative approaches using diet-based natural compounds for the prevention of gastrointestinal cancers.