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AxoSim Technologies

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Year Established:
2014
Website:
axosim.com
Headquarters:
New Orleans, LA, US
Company Type:
Small Business (1-10M TTM Revenue)
Professional Associates:
AAPS, LouisianaBio, SOT
Completed Requests:
12
Open Requests:
4
Certifications:
  • Biosafety Level 2 (BSL 2)
  • Small Business (SB) (unconfirmed)

Utilizing advanced, patent-pending Nerve-on-a-Chip™ technology, AxoSim facilitates preclinical prediction of neurological safety and efficacy early in the drug development pipeline. Employing micro engineering techniques and novel biomaterials, we utilize a 3D human cell-based model which mimics living tissue in both form and function. Deliverable metrics are both structural and functional, determining changes in nerve fiber density, fiber type, myelination level, myelin thickness, as well as population level electrophysiology. Dose and time dependent effects can be measure in near real-time. By providing a tissue engineered alternative to exploratory animal testing, pharmaceutical companies will have access to high content data faster and earlier than currently possible.

Other services include 2D high content imaging and multi-electrode array services. We have extensive expertise with iPSC and primary neuronal cultures and co-cultures with different glia (Schwann cells, astrocytes, etc.) and can perform dose response assays for neurotoxicity applications. In addition, we have done work with disease lines for neurological diseases, (e.g. ALS SOD1).

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AxoSim Technologies
New Orleans BioInnovation Center New Orleans, LA, 70112 United States
AxoSim Maple Grove
13300 67th Avenue North Maple Grove, MN, 55311 United States
AxoSim Maple Grove
13300 67th Avenue North Maple Grove, MN, 55311 United States

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