Axcelead Drug Discovery Partners is the premium CRO in Japan, a spin-out company from Takeda Pharmaceuticals, and provides pharma-standard drug discovery services as your drug discovery engine.

Scope of Business:
・Drug discovery services
Capability:
・Screening : Assay development, HTS, Hit finding, Compound management, Phenotypic screening, AS-MS
・Chemistry: Medicinal Chemistry, Peptide chemistry, Synthetic chemistry, High-throughput synthesis, Analytical chemistry, Computational chemistry, RNA-Targeting Small Molecules, Targeted Protein Degradation
・Biology: oncology, immunology, neuroscience, cardiovascular and metabolism, gastrointestinal motility, cell therapy using large animals, Omics, Bioinformatics, Genetically modified animals, Histopathology, Spatial Transcriptomics, Single cell RNA-seq, Single nucleus RNA-seq
・DMPK: ADME screening, Discovery DMPK studies, Physicochemistry and preformulation, studies
・Safety: In vitro and in vivo exploratory safety studies
・IND/NDA enabling studies
・Target validation/Efficacy studies
・Lead generation/optimization