The HLA and Immunogenetics Laboratory performs DNA-based tissue typing for the Stem Cell Transplant Program at Lurie Children’s. It is accredited, registered or licensed by the following organizations to perform high-complexity testing:
American Society for Histocompatibility and Immunogenetics (ASHI)
Clinical Laboratory Improvement Act of 1988 (CLIA)
National Marrow Donor Program (NMDP)
The services this laboratory provides includes the following:
HLA low-resolution typing by PCR-SSOP: HLA-A, B, C, DRB1, DQA1, DQB1
HLA high-resolution typing by SBT: HLA-A, B, C, DRB1, DQB1
Disease-associated HLA typing: B27, B5701, DQ2, DQ8 et al.
Chimerism analysis by STR
DNA-typing can be performed on peripheral blood, bone marrow, cord blood, or buccal brushes. For your convenience, a special collection kit with instructions can be sent directly to recipients or donors.