AlphaThera specializes in antibody labeling reagents. Their oYo-Link technology enables rapid, covalent, site specific antibody labeling to a wide range of cargos (e.g. oligos, biotin, azide, drugs, click chemistry, and more),in just two-steps and less than than 30 seconds of hands-on time. The reaction is complete in just 2 hours.

The site-specific nature of oYo-Link eliminates the shortcomings that plague conventional protein labeling techniques, such as heterogeneous products, reduced antibody functionality, and batch-to-batch variability. The high affinity, site-specific interaction between oYo-Link and the antibody allows labeling to be performed in all common storage buffers, including those containing Tris and/or BSA, therefore, there is no need to desalt or purify your sample prior to labeling.

Furthermore, oYo-Link enables labeling of as little as 1 µg of antibody at a time and works with antibody concentrations as low as 50 µg/mL. Therefore, you don’t need to concentrate or centrifuge your sample prior to labeling.