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Alliance Pharma

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Year Established:
2008
Website:
resolian.com
Headquarters:
Malvern, PA, US
Company Type:
Mid-Sized Business (10-100M TTM Revenue)
Professional Associates:
AAPS, MassBio, PABio
Completed Requests:
25
Open Requests:
32
Certifications:
  • Clinical Laboratory Improvement Amendments (CLIA)
  • Good Quality Practice (GQP) (unconfirmed)
  • Small Business (SB) (unconfirmed)

The main service that Alliance Pharma provides:

Biopharmaceutical Services (Bioanalytical for Large Molecule/Biologics)

  • Method development, validation and sample analysis for large molecules
  • PK/TK immunoassays (ELISA, ECL, MSD)
  • Immunogenicity assays (ADA) (anti-drug antibody screening, confirmation, titer assessment, and neutralizing antibody (nAb) determination)
  • Cell based bioassays (cytotoxicity, genotoxicity, reporter gene assay, and immunochemistry)
  • Single and multiplex biomarker panels for RNAi, genotyping, gene expression, mutation, and methylation

GLP/Non-GLP Bioanalytical Support

  • LC-MS/MS method development, validation and quantitative analysis of drug and metabolites in biological matrices
  • LC-MS/MS method development, validation and quantitative analysis of proteins and peptides in biological matrices
  • LC-MS/MS protein characterization
  • Evaluation of PK/TK/PD
  • In vivo PK/TK/PD screening
  • In vitro screening
  • Pesticide residue analysis, ILV

In Vitro Drug Metabolism and Drug Transporter Studies

  • Metabolic stability (Intrinsic clearance) in various systems
  • Direct and mechanism-based CYP inhibition
  • CYP induction
  • Reaction phenotyping
  • Drug-drug interactions between small molecules and biologics
  • MDCK/MDCK-MDR1/Caco-2 cell permeability
  • Drug transporter assays for substrates and inhibitors
  • Protein binding in plasma/whole blood/tissues
  • Metabolite profiling, isolation, purification and identification
  • Predictive routes of metabolism and potential toxicity
  • In vitro species comparisons for appropriate pre-clinical animal model selection
  • AAALAC accredited rodent vivarium for discovery PK studies
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Alliance Pharma Inc. DBA Resolian
17 Lee Boulevard Malvern, PA, 19355 United States
Alliance Pharma Inc. DBA Resolian
17 Lee Boulevard Malvern, PA, 19355 United States

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