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Alliance Pharma

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Year Established:
Malvern, PA, US
Company Type:
Mid-Sized Business (10-100M TTM Revenue)
Professional Associates:
AAPS, MassBio, PABio
Completed Requests:
Open Requests:
  • Clinical Laboratory Improvement Amendments (CLIA)
  • Good Quality Practice (GQP) (unconfirmed)
  • Small Business (SB) (unconfirmed)

The main service that Alliance Pharma provides:

Biopharmaceutical Services (Bioanalytical for Large Molecule/Biologics)

  • Method development, validation and sample analysis for large molecules
  • PK/TK immunoassays (ELISA, ECL, MSD)
  • Immunogenicity assays (ADA) (anti-drug antibody screening, confirmation, titer assessment, and neutralizing antibody (nAb) determination)
  • Cell based bioassays (cytotoxicity, genotoxicity, reporter gene assay, and immunochemistry)
  • Single and multiplex biomarker panels for RNAi, genotyping, gene expression, mutation, and methylation

GLP/Non-GLP Bioanalytical Support

  • LC-MS/MS method development, validation and quantitative analysis of drug and metabolites in biological matrices
  • LC-MS/MS method development, validation and quantitative analysis of proteins and peptides in biological matrices
  • LC-MS/MS protein characterization
  • Evaluation of PK/TK/PD
  • In vivo PK/TK/PD screening
  • In vitro screening
  • Pesticide residue analysis, ILV

In Vitro Drug Metabolism and Drug Transporter Studies

  • Metabolic stability (Intrinsic clearance) in various systems
  • Direct and mechanism-based CYP inhibition
  • CYP induction
  • Reaction phenotyping
  • Drug-drug interactions between small molecules and biologics
  • MDCK/MDCK-MDR1/Caco-2 cell permeability
  • Drug transporter assays for substrates and inhibitors
  • Protein binding in plasma/whole blood/tissues
  • Metabolite profiling, isolation, purification and identification
  • Predictive routes of metabolism and potential toxicity
  • In vitro species comparisons for appropriate pre-clinical animal model selection
  • AAALAC accredited rodent vivarium for discovery PK studies
Site Badges
Alliance Pharma Inc. DBA Resolian
17 Lee Boulevard Malvern, PA, 19355 United States
Alliance Pharma Inc. DBA Resolian
17 Lee Boulevard Malvern, PA, 19355 United States

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