Albert Einstein College of Medicine Immune Monitoring Core
Academic Core Facility
Starting with formalin-fixed paraffin embedded tissues, the Immune Monitoring core uses the Vectra Polaris automated slide scanner and NanoString GeoMx Digital Spatial Profiler (DSP) to shed light on the molecular and cellular features of the tumor microenvironment. The Vectra Polaris performs multispectral imaging of 6 markers across 40 slides in a single run. Rapid, unambiguous phenotyping and spatial distribution of immune cells, tumor and stroma can be achieved with minimal hands-on work by the investigator. Spatial RNA sequencing from discrete individual regions of interest comprising a few hundred cells can be accomplished using the GeoMx DSP. This allows the investigator to quantify up to 800 unique transcripts.
Whole slide scanning with multispectral separation
Nanostring nCounter Analyzer
GeoMx digital spatial profiler
|Albert Einstein College of Medicine YU Animal Physiology Core 1300 Morris Park Avenue , NY, 10461 United States|
|Albert Einstein College of Medicine YU Animal Physiology Core Gölding , Oberösterreich, 4631 Austria|
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