Advanced Cellular Dynamics is a leading provider of cutting edge cell-based assay panel technologies and services to the life sciences community. At ACD, we believe that cells provide the ideal context for the discovery of biomedically relevant biological and chemical entities. The ability to develop safe and effective entities that manipulate the dynamics of a targeted protein, while avoiding unintended cellular side-effects, is of great importance to drug discovery researchers worldwide. ACD was established to meet this need by developing and deploying cell-based assay panels that encompass broad representations of pharmaceutically relevant gene families; starting with the kinases. ACD’s cell-based assays allow unprecedented examination of a compound’s functional specificity, enabling the development of highly selective and well-characterized drugs that will speed your drug discovery efforts and help you navigate around previously unforeseeable side effects.

ACD maintains state of the art laboratory suites that are function specific and physically isolated from each other. This encourages an efficient workflow and prevents the unwanted introduction of potentially contaminating materials or reagents between suites. Our molecular biology facility is equipped to handle all aspects of gene isolation (or synthesis), modification, and expression in either prokaryotic or eukaryotic systems. Once constructed, the appropriate reagents are transferred to our tissue culture suite for production of the corresponding cell-based assay system(s). Finally, the assays are transferred to our screening facilities, where we validate their performance and long-term stability prior to incorporating them into our ever growing panel of assays.