Abwiz Bio is at the forefront of pioneering monoclonal antibody development, with a distinctive edge in the intricate processes of antibody humanization and affinity engineering. Utilizing patented technologies for the extraction and amplification of antibody genes from immunized animals, we craft comprehensive antibody libraries and employ cutting-edge phage display techniques for the production of superior monoclonal antibodies.
Our expertise is not only confined to general antibody generation challenges, including those involving complex targets like G protein-coupled receptors (GPCRs) and idiotype antibodies, but also extends to the realm of drug discovery support through the provision of therapeutic antibodies, including those that are challenging to produce against small molecular compounds. We excel in the humanization of antibodies, ensuring that therapeutic candidates are optimally designed for clinical efficacy and reduced immunogenicity.
At Abwiz Bio, we are also adept at eliminating antibodies with unwanted cross-reactivity, thereby enhancing the specificity of the antibodies we develop. This capability is crucial for researchers and developers who require antibodies with high specificity for their unique applications, including the development of diagnostic tools and therapeutic agents.
Our services encompass a wide spectrum of antibody-related needs, from VHH (camelid single-domain antibodies) and antibodies against small molecules to the creation of idiotype antibodies. We specialize in a variety of techniques such as high-throughput screening, single B cell cloning, hybridoma technology, antibody sequencing, conjugation, labeling, and immunoassay development. Our work with humanized animals, mice, rabbits, and human samples, particularly emphasizing the use of rabbits for their diverse antibody repertoire, underscores our ability to tackle even the most formidable challenges in antibody generation, especially for those seeking high affinity and specificity.
Abwiz Bio stands ready to support your endeavors, whether you’re grappling with the production of difficult-to-generate antibodies, seeking to modify antibody affinity for enhanced performance, or requiring specialized antibodies for groundbreaking research or therapeutic interventions. Our comprehensive suite of services is designed to address the full spectrum of your antibody development needs, from discovery through to clinical application.