Our vision is to make biophysics accessible to everyone, accelerating the development of medicines and tools that improve lives and create a happier, healthier, and smarter world.

2bind is a provider for tailor made biophysical analytical services. Since 2011 we have successfully completed > 1400 tasks in contract research projects with > 450 different customers from biotech, pharma, and academia.

2bind serves customers working in protein- and RNA-based drug discovery, antibody development and protein engineering.
2bind offers the perfect service package for all project types and scientific questions. From the ultra-comprehensive analysis of a single molecular interaction with various different technologies to the high-throughput screening of thousands of molecular compounds and fragments. From competition assays to binding analyses in complex biological liquids such as serum, plasma, or cell lysate.

We give researchers, developers, and decision makers the power to accelerate and streamline key research processes.

2bind carries certificates and is technology partner of Creoptix, NanoTemper and Dynamic Biosensors as well as a certificate of Wyatt.

2bind offers outsourcing solutions in
Drug Discovery:
- Protein focused Drug Discovery
- RNA focused Drug Discovery
- Fragment based Drug Discovery
- PROTAC/Glue Discovery

Hit identification:
- Biophysical HTS (150 k compound library)
- Fragment Screening (1920 fragments)
- In silico Screening (2.7 virtual compounds)

Hit Validation

Hit Characterization:
- Affinity
- Thermodynamics
- Kinetics
- Stoichiometry
- Binding in Bioliquids (serum, lysates….)
- compound solubility assays

2bind offers outsourcing solutions in
Antibody Development
- Antibody Developability
- Interaction Studies
- Formulation / Pre-formulation
- Bispecifics

We combine cutting-edge biophysical assay formats such as MST, Spectral Shift, nanoDSF, DLS, BLI, GCI, SEC MALS, HIC, ITC, and the switchSENSE technology (heliX and heliX Cyto) to serve a customer project.
2bind can answer questions on binding affinity, kinetics, thermodynamics, stoichiometry, protein stability, unfolding, buffer optimum, radius, polydispersity index and many more.