Human Bcl-x / BCL2L1 Protein, GST Tag

DESCRIPTION

Bcl-2-like protein 1 (BCL2L1), is also known as Apoptosis regulator Bcl-X (Bcl-XL). BCL2L1 / Bcl-XL is a homodimer protein and belongs to the Bcl-2 family. BCL2L1 is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. BCL2L1 is a potent inhibitor of cell death. BCL2L1 Inhibits activation of caspases. BCL2L1 appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. BCL2L1 / Bcl-XL also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis.

DETAILS

Tag: N-GST
Host: E. coli
Size: 100ug
Buffer: 20 mM Tris, 100 mM NaCl, pH7.5 with 10 mM GSH
Format: Powder
Purity: 92%
Source: Human Bcl-x, GST Tag (BC1-H513a) is expressed from E. coli cells. It contains AA Ser 2 - Arg 212 (Accession # AAH19307).
Storage: -20℃
Category: Bio-Markers & CD Antigens
Molecule: Bcl-x
Accession: AAH19307
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Ser 2 - Arg 212
Swiss-prot: Q07817
Package Size: 100ug*1
Characteristics: This protein carries a GST tag at the N-terminus. The protein has a calculated MW of 50.6 kDa. The protein migrates as 45-50 kDa under reducing (R) condition (SDS-PAGE).
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 50.6 kDa
Shipping Condition: RT
Species Reactivity: Human
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