N6-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)adenosine 3'-CE phosphoramidite

DESCRIPTION:

N6-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)adenosine 3'-CE phosphoramidite is used to incorporate 2'-O-methoxyethyl-modified A into oligonucleotide phosphoramidites, which is useful for antisense RNA. The 2'-MOE backbone provides stronger duplex stability, significant nuclease resistance and relatively low toxicity.

DETAILS

Smiles: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1OCCOC)N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC
Aliases: N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-methoxyethyl)adenosine-3'-O-[(2-cyanoethyl)(N,N-diisopropyl)]-phosphorramidite; N6-Bz-5'-O-DMTr-2'-O-(2-methoxyethyl)-adenosine-3'-CED-phosphoramidite; 2'-O-MOE-A(Bz)-3'-phosphoramidite; N6-Benzoyl-5'-O-DMT-2'-O-MOE-adenosine 3'-CE phosphoramidite; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-(2-methoxyethyl)adenosine; DMT-2'-O-MOE-A(Bz)-CE-Phosphoramidite; N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methoxyethyl-adenosine-3'-cyanoethyl Phosphoramidite
Cas Number: 251647-53-7
Molecular Weight: 932.01
Molecular Formula: C50H58N7O9P