Cynomolgus / Rhesus macaque FGL1 Protein, Mouse IgG2a Fc Tag

DESCRIPTION

Fibrinogen-like protein 1(FGL1) is also known as HP-041, Hepassocin, HFREP-1, LFIRE-1. The protective effect of fibrinogen-like protein 1 (FGL1) in liver injury has previously been reported. However, studies have shown that FGL1 may be a predictor of GC patients and a target for GC therapy. Immunocytochemical studies revealed that fgl1 selectively binds to defective spermatozoa in the cauda epididymidis. Northern blot analysis and in situ hybridization demonstrated the high expression of fgl1 in the principal cells of the proximal cauda epididymidis. Immunofluorescence analysis using mouse fibrotic lung tissues suggested that fibrotic regions showed increased expressions of Gtse1 and Fgl1, Gtse1 and Fgl1 are suggested to be novel targets for radiation-induced lung fibrosis.

DETAILS

Tag: N-mFc(mIgG2a)
Host: HEK293
Size: 1mg
Buffer: 50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH7.5
Format: Powder
Purity: 90%
Source: Cynomolgus / Rhesus macaque FGL1, Mouse IgG2a Fc Tag (FG1-C5250) is expressed from human 293 cells (HEK293). It contains AA Leu 23 - Ile 312 (Accession # G7N0K6-1).
Storage: -20℃
Category: Bio-Markers & CD Antigens
Molecule: FGL1
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Leu 23 - Ile 312
Swiss-prot: G7N0K6-1
Package Size: 500ug*2
Characteristics: This protein carries a mouse IgG2a Fc tag at the N-terminus. The protein has a calculated MW of 60.8 kDa. The protein migrates as 60-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 0.1 EU per μg
Molecular Weight: 60.8 kDa
Shipping Condition: RT
Species Reactivity: Cynomolgus / Rhesus macaque
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