BP3182a
Phospho-Nudel-T245 Antibody Blocking Peptide
Abcepta
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DETAILS
- Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
- Gene Id: 81565
- Category: Peptides; Blocking Peptides
- Subtitle: Synthetic peptide
- Gene Name: NDEL1
- Other Names: Nuclear distribution protein nudE-like 1, Protein Nudel, Mitosin-associated protein 1, NDEL1, EOPA, MITAP1, NUDEL
- Availability: 2 weeks
- Bio Background: Nude1 is a LIS1-interacting protein that participates in the regulation of cytoplasmic dynein heavy chain (CDHC) function via phosphorylation by CDK5/p35. CDHC is a microtubule-based minus-end-directed motor protein that plays an important role in mitotic cell division, neuronal migration, and organelle transport.
- Bio References: Hayashi, M.A., et al., Proc. Natl. Acad. Sci. U.S.A. 102(10):3828-3833 (2005).Morris, J.A., et al., Hum. Mol. Genet. 12(13):1591-1608 (2003).Toyo-oka, K., et al., Nat. Genet. 34(3):274-285 (2003).Yan, X., et al., Mol. Cell. Biol. 23(4):1239-1250 (2003).Ozeki, Y., et al., Proc. Natl. Acad. Sci. U.S.A. 100(1):289-294 (2003).
- Other Accession: Q8TAR7
- Primary Accession: Q9GZM8
- Targetspecificity: The synthetic peptide sequence used to generate the antibody AP3182a was selected from the region of human Phospho-Nudel-T245. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.