CDA-H52H3-50ug CDA-H52H3-1mg
Human CD8 alpha / CD8A Protein, His Tag (MALS verified)
ACROBiosystems
Image
![](https://www.acrobiosystems.com/static/main/products/images/sds/CDA-H52H3.jpg)
Image
![](https://www.acrobiosystems.com/static/main/products/images/elisa/CDA-H52H3-E1.jpg)
Image
![](https://www.acrobiosystems.com/static/main/products/images/elisa/CDA-H52H3-E2.jpg)
Image
![](https://www.acrobiosystems.com/static/main/products/images/elisa/CDA-H52H3-E1.jpg)
DESCRIPTION
Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. In NK-cells, the presence of CD8A homodimers at the cell surface provides a survival mechanism allowing conjugation and lysis of multiple target cells. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells.
DETAILS
- Tag: C-10×His
- Host: HEK293
- Size: 1mg
- Buffer: PBS, pH7.4
- Format: Powder
- Purity: 95%
- Source: Human CD8 alpha, His Tag (CDA-H52H3) is expressed from human 293 cells (HEK293). It contains AA Ser 22 - Asp 182 (Accession # P01732-1).
- Storage: -20℃
- Category: Bio-Markers & CD Antigens
- Molecule: CD8 alpha
- Accession: NP_001759.3
- Conjugate: Unconjugated
- Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
- Exp Region: Ser 22 - Asp 182
- Swiss-prot: P01732-1
- Package Size: 500ug*2
- Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 19.5 kDa. The protein migrates as 26-32 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Endotoxin Level: 0.1 EU per μg
- Molecular Weight: 19.5 kDa
- Shipping Condition: RT
- Species Reactivity: Human
- Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html