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FG4-H51H3-100ug FG4-H51H3-1mg

Human FGF-4 Protein, His Tag

ACROBiosystems

DESCRIPTION

Fibroblast growth factor-4 (FGF4) is expressed in embryonic stages and in adult tissues, where it plays critical roles in modulating multiple cellular functions. Fibroblast growth factor 4 (FGF4) is a multipotent growth factor and is highly expressed in various human cancers. In lung adenocarcinoma (ADC) cell lines, FGF4 could alter cell morphology, promote epithelial-mesenchymal transition-associated protein expression, and enhance cell proliferation, migration/invasion and colony initiation. In B-cell lymphoma, FGF4 secretion by cancer cells induces Jag1 expression in neighbor Endothelial cell that in turn activates Notch2 in lymphoma cells.

DETAILS

  • Tag: C-10×His
  • Host: E. coli
  • Size: 100ug
  • Buffer: MOPS, Na2SO4, Arginine
  • Format: Powder
  • Purity: 90%
  • Source: Human FGF-4 Protein, His Tag (FG4-H51H3) is expressed from E. coli cells. It contains AA Ser 54 - Leu 206 (Accession # P08620-1).
  • Storage: -20℃
  • Category: Cytokines&Growth Factors
  • Molecule: FGF-4
  • Conjugate: Unconjugated
  • Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
  • Exp Region: Ser 54 - Leu 206
  • Swiss-prot: P08620-1
  • Package Size: 100ug*1
  • Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 19.8 kDa. The protein migrates as 23-24 kDa under reducing (R) condition (SDS-PAGE).
  • Endotoxin Level: 1.0 EU per μg
  • Molecular Weight: 19.8 kDa
  • Shipping Condition: RT
  • Species Reactivity: Human
  • Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html