PF-184

DESCRIPTION

PF-184 is a potent, selective inhibitor of IKK-2 with an IC50 value of 37 nM, demonstrating significant selectivity over rhIKK-1, IKKi, and over 30 other tyrosine and serine/threonine kinases. It is utilized in inflammation research, including studies on asthma and chronic obstructive pulmonary disease.

DETAILS

Purity: 98%
Smiles: C[C@@]1([C@](C)(CN(C2=NC=C(Cl)C(C(NC(C=C3)=CC4=C3CCC(C(C(N)=O)=N5)=C4N5C6=CC=C(F)C=C6)=O)=C2)C1)CO)CO
Category: Compound
Molecular Weight: 619.09
Molecular Formula: C32H32ClFN6O4

Lead Time: 5 + weeks