GMP-L04H26-50ug GMP-L04H26-500ug GMP-L04H26-1mg
GMP Human IL-4 Protein
ACROBiosystems
DESCRIPTION
Interleukin-4, is a cytokine that induces differentiation of naive helper T cells (Th0 cells to Th2 cells). In the presence of IL-4 and IL-13, cytokines that are produced in a Th-2 type response, particularly during allergy and parasitic infections, macrophages become differentially activated, And this cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. Recently, researcher found that the cytokine IL-4 plays a key role in development of innate CD8+ T cells in the thymus of several gene-deficient mouse strains, including Itk, KLF2, CBP and Id3, without previous exposure to antigen.
DETAILS
- Tag: Native
- Host: HEK293
- Size: 50ug
- Buffer: PBS, pH7.4
- Format: Powder-GMP
- Purity: 95%
- Source: GMP Human IL-4 Protein (GMP-L04H26) is expressed from human 293 cells (HEK293). It contains AA His 25 - Ser 153 (Accession # P05112-1).
- Storage: -20℃
- Category: Cytokines&Growth Factors
- Molecule: IL-4
- Conjugate: Unconjugated
- Stability: ● -20°C to -70°C for 5 years in lyophilized state; ● -70°C for 12 months under sterile conditions after reconstitution. Upon receipt, store it immediately at -20°C or lower for long term storage.
- Exp Region: His 25 - Ser 153
- Swiss-prot: P05112
- Package Size: 50ug*1
- Characteristics: This protein carries no "tag". The protein has a calculated MW of 15.0 kDa. The protein migrates as 19 kDa±3 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Endotoxin Level: 10 EU/mg
- Molecular Weight: 15.0 kDa
- Shipping Condition: Blue ice
- Species Reactivity: Human
- Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html