Skip to Main Content
Welcome to the Scientist.com Marketplace

Go to Main Navigation

GMP-L04H26-50ug GMP-L04H26-500ug GMP-L04H26-1mg

GMP Human IL-4 Protein

ACROBiosystems

DESCRIPTION

Interleukin-4, is a cytokine that induces differentiation of naive helper T cells (Th0 cells to Th2 cells). In the presence of IL-4 and IL-13, cytokines that are produced in a Th-2 type response, particularly during allergy and parasitic infections, macrophages become differentially activated, And this cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. Recently, researcher found that the cytokine IL-4 plays a key role in development of innate CD8+ T cells in the thymus of several gene-deficient mouse strains, including Itk, KLF2, CBP and Id3, without previous exposure to antigen.

DETAILS

  • Tag: Native
  • Host: HEK293
  • Size: 50ug
  • Buffer: PBS, pH7.4
  • Format: Powder-GMP
  • Purity: 95%
  • Source: GMP Human IL-4 Protein (GMP-L04H26) is expressed from human 293 cells (HEK293). It contains AA His 25 - Ser 153 (Accession # P05112-1).
  • Storage: -20℃
  • Category: Cytokines&Growth Factors
  • Molecule: IL-4
  • Conjugate: Unconjugated
  • Stability: ● -20°C to -70°C for 5 years in lyophilized state; ● -70°C for 12 months under sterile conditions after reconstitution. Upon receipt, store it immediately at -20°C or lower for long term storage.
  • Exp Region: His 25 - Ser 153
  • Swiss-prot: P05112
  • Package Size: 50ug*1
  • Characteristics: This protein carries no "tag". The protein has a calculated MW of 15.0 kDa. The protein migrates as 19 kDa±3 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Endotoxin Level: 10 EU/mg
  • Molecular Weight: 15.0 kDa
  • Shipping Condition: Blue ice
  • Species Reactivity: Human
  • Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html