36278
γ-D-Glutamylglycine (trifluoroacetate salt)
Cayman Chemical
DESCRIPTION
An excitatory amino acid antagonist; decreases the amplitude of EPSPs in electrically stimulated rat hippocampal slices at 200 mM; subdural administration inhibits NMDA-, kainate-, or quisqualate-induced paw biting, indicating antinociceptive activity, in mice (EC50s = 63, 9.5, and 31 µM, respectively); reduces sound-induced wild running and inhibits the clonic and tonic phases of sound-induced seizures in DBA/2 mice (ED50s = 0.058, 0.046, and 0.054 µmol, i.c.v., respectively)
DETAILS
- Inchi: InChI=1S/C7H12N2O5.C2HF3O2/c8-4(7(13)14)1-2-5(10)9-3-6(11)12;3-2(4,5)1(6)7/h4H,1-3,8H2,(H,9,10)(H,11,12)(H,13,14);(H,6,7)/t4-;/m1./s1
- Purity: ≥95%
- Raptas: Product Type|Biochemicals|Peptides||Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Research Area|Neuroscience|Pain Research||Research Area|Neuroscience|Seizure Disorders
- Smiles: OC(CNC(CC[C@@H](N)C(O)=O)=O)=O.FC(F)(C(O)=O)F
- Inchikey: UBOUYYUIWKVKPI-PGMHMLKASA-N
- Cas Number: 71822-19-0
- Formulation: A solid
- Storage Temp: -20
- Shipping Temp: -20
- Formula Markup: C7H12N2O5 • CF3COOH
- Formula Weight: 318.2
- Shelf Life Days: 1460
Equivalent Items
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