Human TSLP (R127A, R130A) Protein, His Tag (MALS verified)

DESCRIPTION

Thymic stromal lymphopoietin (TSLP) is an epithelial cell-derived cytokine involved in the pathology of inflammatory skin diseases, and is widely expressed by epithelial cells. Human TSLP cDNA encodes a 159 amino acid (aa) residue precursor protein with a 28 aa signal sequence (4, 5). Human TSLP has been shown to developing nondeletional central tolerance, amplifying epithelium-induced class switching, inducing atopic diseases and maintaining intestinal noninflammatory environment. Among diverse cells responding to Human TSLP, CD11c+ dendritic cells are the most obviously characterized target cells.

DETAILS

Tag: C-10×His
Host: HEK293
Size: 1mg
Buffer: PBS, pH7.4
Format: Powder
Purity: 90%
Source: Human TSLP (R127A, R130A) Protein, His Tag (TSP-H52Ha) is expressed from human 293 cells (HEK293). It contains AA Tyr 29 - Gln 159 (Accession # Q969D9-1 (R127A, R130A)).
Storage: -20℃
Category: Other Recombinant Proteins
Molecule: TSLP
Accession: NP_149024.1 (R127A, R130A)
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Tyr 29 - Gln 159
Swiss-prot: Q969D9-1 (R127A, R130A)
Package Size: 500ug*2
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 16.7 kDa. The protein migrates as 25-29 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 16.7 kDa
Shipping Condition: RT
Species Reactivity: Human
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