28714
Scientist.com Supplier
GGTI 2418
Cayman Chemical
DESCRIPTION
An inhibitor of GGTase I (IC50 = 9.5 nM); selective for GGTase I over FTase (IC50 = 53,000 nM); reduces tumor growth in an MDA-MB-231 breast cancer mouse xenograft model at 100 mg/kg
DETAILS
- Inchi: InChI=1S/C23H31N5O4/c1-15(2)11-18(22(30)31)26-23(32)28-10-9-27(13-19-16(3)24-14-25-19)21(29)20(28)12-17-7-5-4-6-8-17/h4-8,14-15,18,20H,9-13H2,1-3H3,(H,24,25)(H,26,32)(H,30,31)/t18-,20-/m0/s1
- Purity: ≥98%
- Raptas: Product Type|Biochemicals|Small Molecule Inhibitors|Acyltransferases||Research Area|Cancer
- Smiles: O=C1[C@H](CC2=CC=CC=C2)N(C(N[C@H](C(O)=O)CC(C)C)=O)CCN1CC3=C(C)N=CN3
- Inchikey: COLCNDRDBCLVOC-ICSRJNTNSA-N
- Cas Number: 501010-06-6
- Formulation: A crystalline solid
- Storage Temp: -20
- Shipping Temp: -20
- Formula Markup: C23H31N5O4
- Formula Weight: 441.5
- Shelf Life Days: 1460