Human Tau-441 K18 Pre-formed Fibrils Protein, His Tag

DESCRIPTION

Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease, frontotemporal dementia, and other tauopathies.

DETAILS

Tag: N-6×His
Host: E. coli
Size: 500ug
Buffer: PBS, pH7.4
Format: Liquid
Purity: 90%
Source: Human Tau-441 K18 Pre-formed Fibrils Protein, His Tag (TAU-H5146) is expressed from E. coli cells. It contains AA Gln 244 - Glu 372 (Accession # P10636-8).
Storage: -70℃
Category: Other Recombinant Proteins
Molecule: Tau
Conjugate: Unconjugated
Stability: ● The product should be stored at -70°C or room temperature for short storage. Do not store fibrils on ice or at 4°C; ● The unsonicated fibril is validated to be stable after storage at -70°C for 1 year under sterile conditions; ● The sonicated fibril should be stored at -70°C for not more than 8 weeks.
Exp Region: Gln 244 - Glu 372
Package Size: 500ug*1
Characteristics: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 13.8 kDa.
Endotoxin Level: 0.05 EU per μg
Molecular Weight: 13.8 kDa
Shipping Condition: Dry ice
Species Reactivity: Human
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