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HY-145737A

Scientist.com Supplier

PROTAC SOS1 degrader-1 (TFA)

MedChem Express

- Open Babel Depiction H 3 C N S H 3 C N H O OH F CH 3 Cl H 3 C CH 3 CH 3 N N HN N N N O NH O CH 3 N
DESCRIPTION:
PROTAC SOS1 degrader-1 (TFA) is a potent PROTAC SOS1 degrader with an DC50 of 98.4 nM. PROTAC SOS1 degrader-1 shows antiproliferation activity in cancer cells with various KRAS mutations. PROTAC SOS1 degrader-1 shows antitumor effect with low toxicity[1].

DETAILS

  • Purity: >98%
  • Smiles: O=C([C@H]1N(C([C@@H](NC(CCCCCCCCN2CCN(C3=C4C(N(CC5=CC(C)=C(F)C(C)=C5)C(N6CC7(CNC7)C6)=N4)=CC(Cl)=C3)CC2)=O)C(C)(C)C)=O)C[C@H](O)C1)N[C@H](C8=CC=C(C9=C(C)N=CS9)C=C8)C.OC(C(F)(F)F)=O
  • Category: Reference compound
  • Lead Time: 1-2 days
  • Molecular Weight: 1165.82
  • Molecular Formula: C59H77ClF4N10O6S

Lead Time: < 1 week

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