Human IgG4 Fc Protein, Tag Free (MALS & SPR verified)

DESCRIPTION

Immunoglobulin G4 (IgG4) is a member of many immunoglobulin G developed and secreted by effective B cells. In wake of cutting by pepsin, IgG is divided into two F(ab)s with one antigen binding site and a high conserved Fc segment. The Fc segment bears a highly conserved N-glycosylation site. Ig gamma-4 chain Fc region contains two constant regions of IgG4 H chain (CH2, CH3).

DETAILS

Tag: Native
Host: HEK293
Size: 200ug
Buffer: Tris with Glycine, Arginine and NaCl, pH7.5
Format: Powder
Purity: 95%
Source: Human IgG4 Fc, Tag Free (IG4-H5205) is expressed from human 293 cells (HEK293). It contains AA Glu 99 - Lys 327 (Accession # P01861).
Storage: -20℃
Category: Other Recombinant Proteins
Molecule: IgG4 Fc
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Glu 99 - Lys 327
Swiss-prot: P01861
Package Size: 200ug*1
Characteristics: This protein carries no "tag". The protein has a calculated MW of 25.8 kDa. The protein migrates as 30-32 kDa under reducing (R) condition, and 28-30 kDa and 55-60 kDa under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 25.8 kDa
Shipping Condition: RT
Species Reactivity: Human
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