MU1-H5256-100ug MU1-H5256-1mg
Human Mucin-1 / MUC-1 (116-173) Protein, Fc Tag
ACROBiosystems
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DESCRIPTION
Membrane mucins have several functions in epithelial cells including cytoprotection, extravasation during metastases, maintenance of luminal structure, and signal transduction. MUC17, contains an extended, repetitive extracellular glycosylation domain and a carboxyl terminus with two EGF-like domains, a SEA module domain, a transmembrane domain, and a cytoplasmic domain with potential serine and tyrosine phosphorylation sites. Interacts via its C-terminus with PDZK1 and this interaction appears important for proper localization. Probably plays a role in maintaining homeostasis on mucosal surfaces.
DETAILS
- Tag: C-Fc
- Host: HEK293
- Size: 1mg
- Buffer: PBS, pH7.4
- Format: Powder
- Purity: 95%
- Source: Human Mucin-1 (116-173), Fc Tag (MU1-H5256) is expressed from human 293 cells (HEK293). It contains AA Ser 116 - Gly 173 (Accession # P15941-8).
- Storage: -20℃
- Category: Bio-Markers & CD Antigens
- Molecule: Mucin-1
- Accession: NP_002447.4
- Conjugate: Unconjugated
- Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
- Exp Region: Ser 116 - Gly 173
- Swiss-prot: P15941-8
- Package Size: 500ug*2
- Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 32.7 kDa. The protein migrates as 40-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Endotoxin Level: 1.0 EU per μg
- Molecular Weight: 32.7 kDa
- Shipping Condition: RT
- Species Reactivity: Human
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