Cynomolgus Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein, His Tag&Tag Free

DESCRIPTION

Integrin alpha-V/beta-3 (ITGAV:ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrins alpha-IIb/beta-3 and alpha-V/beta-3 recognize the sequence R-G-D in a wide array of ligands. Also, Integrin alpha-V/beta-3 acts as a receptor for herpes virus 8/HHV-8, coxsackievirus A9, Hantaan virus, cytomegalovirus/HHV-5, human metapneumovirus, human parechovirus 1 and west nile virus. Furthermore, in case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.

DETAILS

Tag: C-10×His | Native
Host: HEK293
Size: 100ug
Buffer: 50 mM Tris, 150 mM NaCl, pH8.0
Format: Powder
Purity: 90%
Source: Cynomolgus Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein, His Tag&Tag Free (IT3-C52W3) is expressed from human 293 cells (HEK293). It contains AA Phe 31 - Pro 993 & Gly 27 - Asp 718 (Accession # A0A2K5WCD3-1 & A0A2K5WYN9).
Storage: -20℃
Category: Bio-Markers & CD Antigens
Molecule: Integrin alpha V beta 3
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Phe 31 - Pro 993 & Gly 27 - Asp 718
Swiss-prot: A0A2K5WCD3-1 | A0A2K5WYN9
Package Size: 100ug*1
Characteristics: Cynomolgus Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein, His Tag&Tag Free, produced by co-expression of ITGAV and ITGB3, has a calculated MW of 113 kDa (ITGAV) and 81.7 kDa (ITGB3). The protein migrates as 90 kDa and 150 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 113 kDa & 81.7kDa
Shipping Condition: RT
Species Reactivity: Cynomolgus
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