MDFIC Antibody (N-term) Blocking Peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 29969
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: MDFIC
Other Names: MyoD family inhibitor domain-containing protein, I-mfa domain-containing protein, hIC, MDFIC (HGNC:28870)
Availability: 2 weeks
Bio Background: MDFIC is a member of a family of proteins characterized by a specific cysteine-rich C-terminal domain, which is involved in transcriptional regulation of viral genome expression. Alternative translation initiation from an upstream non-AUG (GUG), and an in-frame, downstream AUG codon, results in the production of two isoforms, p40 and p32, respectively, which have different subcellular localization; p32 is mainly found in the cytoplasm, whereas p40 is targeted to the nucleolus.
Bio References: Thebault,S. et.al., Curr. Protein Pept. Sci. 2 (2), 155-167 (2001)
Primary Accession: Q9P1T7
Targetspecificity: The synthetic peptide sequence used to generate the antibody AP8709a was selected from the N-term region of human MDFIC. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.