Mouse CD38 Protein, His Tag

DESCRIPTION

CD antigen CD38 is also known as ADP-ribosyl cyclase 1, which belongs to the ADP-ribosyl cyclase family. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2+. The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism. CD38 has been used as a prognostic marker in leukemia.

DETAILS

Tag: C-10×His
Host: HEK293
Size: 1mg
Buffer: 50 mM MES, 100 mM NaCl, pH6.5
Format: Powder
Purity: 90%
Source: Mouse CD38, His Tag (CD8-M5223) is expressed from human 293 cells (HEK293). It contains AA Leu 45 - Thr 304 (Accession # P56528-1).
Storage: -20℃
Category: Bio-Markers & CD Antigens
Molecule: CD38
Accession: NP_031672.2
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Leu 45 - Thr 304
Swiss-prot: P56528-1
Package Size: 250ug*4
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 31.7 kDa. The protein migrates as 38-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 31.7 kDa
Shipping Condition: RT
Species Reactivity: Mouse
Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html