SLCO3A1 Antibody (Center) Blocking Peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 28232
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: SLCO3A1
Other Names: Solute carrier organic anion transporter family member 3A1, OATP3A1, Organic anion transporter polypeptide-related protein 3, OATP-RP3, OATPRP3, Organic anion-transporting polypeptide D, OATP-D, PGE1 transporter, Sodium-independent organic anion transporter D, Solute carrier family 21 member 11, SLCO3A1, OATP3A1, OATPD, SLC21A11
Availability: 2 weeks
Bio Background: SLCO3A1 mediates the Na(+)-independent transport of organic anions such as estrone-3-sulfate (PubMed:10873595). Mediates transport of prostaglandins (PG) E1 and E2, thyroxine (T4), deltorphin II, BQ-123 and vasopressin, but not DPDPE (a derivative of enkephalin lacking an N-terminal tyrosine residue), estrone-3-sulfate, taurocholate, digoxin nor DHEAS (PubMed:16971491).
Bio References: Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Volpi, S., et al. Mol. Psychiatry 14(11):1024-1031(2009)Montasser, M.E., et al. J. Hypertens. 27(3):491-501(2009)Lasky-Su, J., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 147B (8), 1345-1354 (2008) :Huber, R.D., et al. Am. J. Physiol., Cell Physiol. 292 (2), C795-C806 (2007) :
Primary Accession: Q9UIG8
Targetspecificity: The synthetic peptide sequence used to generate the antibody AP13144c was selected from the Center region of SLCO3A1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.